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This article is part of the supplement: Focus on Bovine Mastitis: knowledge into practice

Open Access Highly Accessed Review

Changing trends in mastitis

RN Zadoks* and JL Fitzpatrick

Author Affiliations

Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, EH26 0PZ Scotland, UK

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Irish Veterinary Journal 2009, 62(Suppl 4):S59-70  doi:10.1186/2046-0481-62-S4-S59

Published: 1 April 2009

Abstract

The global dairy industry, the predominant pathogens causing mastitis, our understanding of mastitis pathogens and the host response to intramammary infection are changing rapidly. This paper aims to discuss changes in each of these aspects. Globalisation, energy demands, human population growth and climate change all affect the dairy industry. In many western countries, control programs for contagious mastitis have been in place for decades, resulting in a decrease in occurrence of Streptococcus agalactiae and Staphylococcus aureus mastitis and an increase in the relative impact of Streptococcus uberis and Escherichia coli mastitis. In some countries, Klebsiella spp. or Streptococcus dysgalactiae are appearing as important causes of mastitis. Differences between countries in legislation, veterinary and laboratory services and farmers' management practices affect the distribution and impact of mastitis pathogens. For pathogens that have traditionally been categorised as contagious, strain adaptation to human and bovine hosts has been recognised. For pathogens that are often categorised as environmental, strains causing transient and chronic infections are distinguished. The genetic basis underlying host adaptation and mechanisms of infection is being unravelled. Genomic information on pathogens and their hosts and improved knowledge of the host's innate and acquired immune responses to intramammary infections provide opportunities to expand our understanding of bovine mastitis. These developments will undoubtedly contribute to novel approaches to mastitis diagnostics and control.

Keywords:
bovine; genetics; host; mastitis; molecular typing; pathogen